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Acute Hepatitis C Virus Infections Attributed to Unsafe Injection Practices at an Endoscopy Clinic - Nevada, 2007 (State of Nevada)

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eBook details

  • Title: Acute Hepatitis C Virus Infections Attributed to Unsafe Injection Practices at an Endoscopy Clinic - Nevada, 2007 (State of Nevada)
  • Author : Nevada RNformation
  • Release Date : January 01, 2008
  • Genre: Health & Fitness,Books,Health, Mind & Body,Business & Personal Finance,Industries & Professions,
  • Pages : * pages
  • Size : 84 KB

Description

On January 2, 2008, the Nevada State Health Division (NSHD) contacted CDC concerning surveillance reports received by the Southern Nevada Health District (SNHD) regarding two persons recently diagnosed with acute hepatitis C. A third person with acute hepatitis C was reported the following day. This raised concerns about an outbreak because SNHD typically confirms four or fewer cases of acute hepatitis C per year. Initial inquiries found that all three persons with acute hepatitis C underwent procedures at the same endoscopy clinic (clinic A) within 35-90 days of illness onset. A joint investigation by SNHD, NSHD, and CDC was initiated on January 9, 2008. The epidemiologic and laboratory investigation revealed that hepatitis C virus (HCV) transmission likely resulted from reuse of syringes on individual patients and use of single-use medication vials on multiple patients at the clinic. Health officials advised clinic A to stop unsafe injection practices immediately, and approximately 40,000 patients of the clinic were notified about their potential risk for exposure to HCV and other bloodborne pathogens. This report focuses on the six cases of acute hepatitis C identified during the initial investigation, which is ongoing; additional cases of acute hepatitis C associated with exposures at clinic A might be identified. Comprehensive measures involving viral hepatitis surveillance, health-care provider education, public awareness, professional oversight, licensing, and improvements in medical devices can help detect and prevent transmission of HCV and other bloodborne pathogens in health-care settings. The objectives of the investigation were to conduct case-finding and review health histories of infected persons, to determine the source of transmission and implement control measures, to identify other patients at risk for exposure, and to assist in development of recommendations to prevent HCV transmission in health-care settings. Persons with acute hepatitis C were interviewed, and blood samples were obtained after these persons gave oral consent. Blood samples were sent to CDC for testing for HCV genotype at the NS5b region and phylogenetic relatedness at the hypervariable 1 region (HVR1) to help determine whether a common source of transmission existed (1). Specimens also were tested for other bloodborne infections (hepatitis B virus [HBV]) and human immunodeficiency virus [HIV]). Case-finding activities included SNHD's review of acute hepatitis C surveillance records, cross-matching of local HCV laboratory records with clinic A procedure logs, review of medical records for patients who underwent procedures at clinic A on the same day as HCV-infected persons, and serologic HCV, HBV, and HIV testing of staff. An extensive review of the clinic practices and procedures also was conducted, including observation of several endoscopic procedures and endoscopic reprocessing, observation of anesthesia practices, and interviews with staff members regarding their infection-control practices.


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